Sakae Tanaka MD, PhD graduated from University of Tokyo in 1987. He learned osteoclast biology in Department of Biochemistry, Showa University School of Dentistry from 1990 to 1993 and worked as a postdoctoral associate in Department of Cell Biology, Yale University School of Medicine from 1993 to 1995. He has been serving as Professor in the Department of Orthopaedic Surgery, Faculty of Medicine, the University of Tokyo since 2012. He has more than 300 international publications, 50 international presentations in international congresses and more than 13,000 citations in indexed international scientific journals. His clinical specialty is joint surgery and clinical interest includes rheumatoid arthritis and osteoporosis. His scientific fields of interest are osteoclast biology, signal transduction and apoptosis.