• Kristen Demoruelle

    Assistant Professor of Medicine, Division of Rheumatology/University of Colorado in Aurora, Colorado

  • Dr. Kristen Demoruelle, MD, PhD, is a rheumatologist and translational research scientist whose research focuses on understanding the development of RA-related autoimmunity prior to the onset of joint disease during the ‘pre-clinical’ phase of RA development. Her research investigates the central hypothesis that autoimmunity in RA, including antibodies to citrullinated protein antigens (ACPA), is initially generated at a mucosal surface, such as the lung or female genital tract, in relation to local mucosal factors such as microbiota or neutrophil extracellular trap (NET) formation. Her work in this area has been a major factor leading to the current understanding that mucosal sites likely play an important role in the pathogenesis of RA.